Taylor, a 26-year-old EMT, was shot multiple times in March by police who were executing a no-knock warrant at her apartment.
The billboard featured a portrait of Taylor that is on the cover of the September issue of the magazine. It’s the first time Winfrey was not featured on the cover of her namesake magazine in its 20-year history.
Louisville Metro Police Sgt. Lamont Washington told CNN on Wednesday officers went to the Irish Hill neighborhood to inspect the billboard at about 3 p.m. after hearing about the vandalism on social media.
The billboard had been cleaned or replaced by the time officers arrived, Washington said.
Washington said that police would talk to the billboard company to see if they wanted to file a report.
None of the officers involved in the March 13 shooting have been charged.
CORRECTION: This story has been updated to reflect that the September issue of O Magazine marks the first time Winfrey has not been featured on the publication’s cover.