Some mass vaccination sites in U.S. begin to close as some demand falls.

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In the first few months of the year, the site in the county of 41,000, which borders Indiana, would fill up its 400 appointments in an hour or two, he said. “We could even reach down into those who were not age-eligible to get it to come in at the end of the day to come out quickly and get it into someone’s arm,” he said.

But demand has fallen precipitously in the last several weeks, and last week the county ended up wasting two doses, which was a first. “We no longer have a reserve of people who want to be vaccinated to reach into to show up and take those doses,” he added.

The largest vaccination site in Las Vegas, the Cashman Center, will close on May 5 as the list of open appointments grow and the lines to be inoculated have dwindled. The tens of thousands of open appointments at sites across the nation are forcing officials to pivot their outreach strategies and zero in on smaller events.

Palm Beach County in Florida said on Tuesday that it would shut its three mass vaccination sites, which are operating at about half capacity, by the end of May. Of 16,000 appointment slots available this week, only 6,000 were filled, according to health officials. Instead, three mobile units will each aim to give 500 doses a day.

In Galveston County, Texas, a mass drive-through clinic at a county park won’t operate after May 1. The park has been administering 5,000 doses per day, including on Thursday. But demand for appointments has dampened in the last three weeks, according to the county’s chief public health officer. He also asked the state to pause vaccine shipments.

“We’re concerned that some of it may expire before we use it, if we keep getting it,” said Dr. Philip Keiser. “We are trying to figure out how to balance out supply and demand, yet also have enough on hand so that when school kids are able to get back, we can do them.”

There will be much more targeted outreach, down to the Census tract level, Dr. Keiser said, and there might be 100 or 200 injections per day rather than thousands.

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